Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT02864485	TitleLiving Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases	Phase Not Applicable	Date Added 2016-08-12	Location Canada	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03494946	TitleLiver Transplantation Compared to Chemotherapy in Patients With ColoRectal Cancer	Phase Not Applicable	Date Added 2018-04-11	Location Norway	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Chemotherapy	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03796884	TitleLinaclotide in Treating Patients With Stages 0-3 Colorectal Cancer	Phase Phase 2	Date Added 2019-01-08	Location Pennsylvania, United States Washington, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Linaclotide	Tags MSS/ MMRp
NCT ID NCT06099821	TitleKN046 Plus Regorafenib or Apatinib in MSI-H Digestive System Cancers Resistant to PD-1/PD-L1 Blockade	Phase Phase 2	Date Added 2023-10-25	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs apatinib, KN046, Regorafenib	Tags MSI-H/ MMRd
NCT ID NCT03667170	TitleKN035 for dMMR/MSI-H Advanced Solid Tumors	Phase Phase 2	Date Added 2018-09-12	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd
NCT ID NCT06634875	TitleIsunakinra Alone and in Combination with Pembrolizumab in Patients with Colorectal Cancer (MSS)	Phase Phase 2	Date Added 2024-10-10	Location California, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT03867799	TitleiSCORE: Immunotherapy Sequencing in COlon and REctal Cancer	Phase Phase 2	Date Added 2019-03-08	Location United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Nivolumab	Tags MSS/ MMRp
NCT ID NCT06047015	TitleIrreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment of Stage IV Colorectal Cancer	Phase Phase 1	Date Added 2023-09-21	Location	Prior IO Allowed Yes	CRC-directed Yes	Status Not yet recruiting	Drugs	Tags MSS/ MMRp
NCT ID LUMINESCENCE	TitleIpilimumab, Maraviroc and Nivolumab (LUMINESCENCE)	Phase Phase 1	Date Added 2019-01-25	Location	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Ipilimumab, maraviroc, Nivolumab, Celsentri, Opdivo, Selzentry, Yervoy	Tags MSS/ MMRp
NCT ID NCT02668770	TitleIpilimumab (Immunotherapy) and MGN1703 (TLR Agonist) in Patients With Advanced Solid Malignancies	Phase Phase 1	Date Added 2016-01-29	Location Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Ipilimumab, MGN1703	Tags MSS/ MMRp

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