Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT05609370	TitleA Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Capecitabine Versus Bevacizumab Plus Capecitabine in Participants With Unresectable or Metastatic Colorectal Cancer	Phase Phase 1, Phase 2	Date Added 2022-11-08	Location Alaska, United States Arizona, United States California, United States Florida, United States Indiana, United States Kentucky, United States Louisiana, United States Missouri, United States Montana, United States Nevada, United States New Mexico, United States New York, United States North Carolina, United States Tennessee, United States Texas, United States Virginia, United States Washington, United States Australia China Puerto Rico	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Bevacizumab, capecitabine, LBL-007, Tislelizumab	Tags MSS/ MMRp
NCT ID NCT04085185	TitleA Study Evaluating the Safety, Tolerability, and Initial Efficacy of IBI110 in Subjects With Advanced Malignant Tumors	Phase Phase 1	Date Added 2019-09-11	Location China	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs IBI110, IBI110+ Sintilimab, IBI110, Sintilinab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04009681	TitleA Study Evaluating Safety and Therapeutic Activity of THOR-707 in Adult Subjects With Advanced or Metastatic Solid Tumors	Phase Phase 1	Date Added 2019-07-05	Location Arizona, United States Colorado, United States Florida, United States Tennessee, United States Texas, United States Argentina Australia Chile Singapore Spain	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs anti-EGFR antibody, Checkpoint inhibitor, THOR-707	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05653882	TitleA Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors	Phase Phase 1	Date Added 2022-12-16	Location California, United States Connecticut, United States Florida, United States Massachusetts, United States Michigan, United States Missouri, United States New Jersey, United States New York, United States North Carolina, United States Tennessee, United States Virginia, United States	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05491317	TitleA Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid Tumors	Phase Phase 1, Phase 2	Date Added 2022-08-08	Location France	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Pembrolizumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06513221	TitleA Prospective Study of MSS-type Metastatic Colorectal Cancer Receiving Multiple Lines of Standard Chemotherapy, Bevacizumab Combined With Adebrelimab	Phase	Date Added 2024-07-22	Location	Prior IO Allowed No	CRC-directed Yes	Status	Drugs	Tags MSS/ MMRp
NCT ID NCT03981146	TitleA Phase II Trial Assessing Nivolumab in Class II Expressing Microsatellite Stable Colorectal Cancer	Phase Phase 2	Date Added 2019-06-10	Location United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Nivolumab, Opdivo	Tags MSS/ MMRp
NCT ID NCT05205330	TitleA Phase Ib/IIa Study of CR6086 in Combination With Balstilimab in pMMR-MSS Metastatic Colorectal Cancer Patients	Phase Phase 2	Date Added 2022-01-25	Location Italy	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs AGEN2034, Balstilimab, CR6086	Tags MSS/ MMRp
NCT ID NCT04550897	TitleA Phase I/II Study With BM7PE Immunotoxin in Colorectal Cancer Patients	Phase Phase 1	Date Added 2020-09-16	Location Norway	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs BM7PE	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06508307	TitleA Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors	Phase Phase 1	Date Added 2024-07-18	Location China	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp

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