Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT06788171	TitlePULSAR Combined With PD-1 Ab and Chemotherapy Plus Bev. for CRLM	Phase Phase 2	Date Added 2025-03-25	Location China	Prior IO Allowed No	CRC-directed Yes	Status Not yet recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT03650348	TitlePRS-343 in Combination With Atezolizumab in HER2-Positive Solid Tumors	Phase Phase 1	Date Added 2018-08-28	Location California, United States Louisiana, United States New York, United States Ohio, United States Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs PRS-343 in Combination with Atezolizumab, Tecentriq	Tags MSS/ MMRp
NCT ID NCT01697371	TitleProton Therapy in the Treatment of Liver Metastases	Phase Not Applicable	Date Added 2012-10-02	Location California, United States	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06120127	TitlePostoperative Chemotherapy With/Without Radiotherapy and Immunotherapy for Colorectal Liver Metastases With High Risk of Locally Recurrence	Phase Phase 2	Date Added 2023-11-07	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Chemotherapy, PD-1 antibody	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04117087	TitlePooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected MMR-p Colorectal and Pancreatic Cancer	Phase Phase 1	Date Added 2019-10-07	Location Maryland, United States	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Ipilimumab, Nivolumab, Opdivo, Yervoy	Tags MSS/ MMRp
NCT ID NCT06300463	TitlePlatform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases	Phase Phase 2	Date Added 2024-03-08	Location New York, United States	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs AGEN1423, Balstilimab, Botensilimab	Tags MSS/ MMRp
NCT ID NCT03868228	TitlePIPAC for the Treatment of Colorectal Peritoneal Metastases	Phase Phase 1	Date Added 2019-03-11	Location United Kingdom	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04708470	TitlePhase I/II Trial of the Combination of Bintrafusp Alfa (M7824), Entinostat and NHS-IL12 (M9241) in Patients With Advanced Cancer	Phase Phase 1, Phase 2	Date Added 2021-01-14	Location Maryland, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Bintrafusp alfa, Entinostat, NHS-IL12	Tags MSS/ MMRp
NCT ID NCT06149481	TitlePhase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)	Phase Phase 1, Phase 2	Date Added 2023-11-29	Location Maryland, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs N-803, Retifanlimab, SX-682	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02484404	TitlePhase I/II Study of the Anti-Programmed Death Ligand-1 Durvalumab Antibody (MEDI4736) in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Can…	Phase Phase 1, Phase 2	Date Added 2015-06-29	Location Maryland, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Cediranib, durvalumab, Olaparib	Tags MSI-H/ MMRd, MSS/ MMRp

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