Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT06218914	TitleA Study of NT-112 in HLA-C*08:02-Positive Adult Subjects With Unresectable, Advanced, and/ or Metastatic Solid Tumors Positive for the KRAS G12D Mutation	Phase Phase 1	Date Added 2024-01-23	Location California, United States Florida, United States Illinois, United States Kansas, United States Missouri, United States New York, United States Pennsylvania, United States Tennessee, United States Texas, United States Washington, United States Wisconsin, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05999812	TitleClinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer	Phase Phase 2	Date Added 2023-08-21	Location Texas, United States	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs all trans Retinoic Acid, Atezolizumab, Bevacizumab	Tags MSS/ MMRp
NCT ID NCT06008119	TitleEfficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer	Phase Phase 3	Date Added 2023-08-23	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Doublets Chemotherapy ± Bevacizumab or Doublets Chemotherapy ± Cetuximab, Tunlametinib plus Vemurafenib	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06006923	TitleRegorafenib in Combination With Pembrolizumab or Pembrolizumab for MSI-H Colorectal Cancer	Phase Phase 2	Date Added 2023-08-23	Location California, United States Florida, United States Illinois, United States Michigan, United States Pennsylvania, United States Washington, United States	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Pembrolizumab, Regorafenib, Keytruda, Stivarga	Tags MSI-H/ MMRd
NCT ID NCT06010901	TitleA Clinical Study of TQB2618 Injection Monotherapy and Combination Regimen (With Penpulimab Injection ±Anlotinib Hydrochloride Capsules) in the Four or Later Lines of Treatment of Advanced Colorectal Cancer.	Phase Phase 1	Date Added 2023-08-25	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Anlotinib hydrochloride capsules, Penpulimab Injection, TQB2618 injection	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06014502	TitleStudy to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors	Phase Phase 1	Date Added 2023-08-28	Location Arizona, United States California, United States Louisiana, United States Texas, United States	Prior IO Allowed No	CRC-directed No	Status Recruiting	Drugs IMGS-001	Tags MSI-H/ MMRd
NCT ID NCT06013111	TitleAn Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti-CEA-CAR-T Cells Injection in Patients With CEA+ Locally Advanced and/or Metastatic Solid Tumors	Phase Phase 1	Date Added 2023-08-28	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06149481	TitlePhase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)	Phase Phase 1, Phase 2	Date Added 2023-11-29	Location Maryland, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs N-803, Retifanlimab, SX-682	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06026774	TitleClinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms	Phase Phase 1	Date Added 2023-09-07	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06055439	TitleA Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy	Phase Phase 1, Phase 2	Date Added 2023-09-26	Location Georgia, United States Illinois, United States Pennsylvania, United States Tennessee, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp

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