Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT01351103	TitleA Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands	Fase Fase 1	Date Added 2011-05-10	Ubicación California, United States Maryland, United States Massachusetts, United States Michigan, United States Texas, United States Canadá Francia Alemania Italia Países Bajos España	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas LGK974, PDR001	Etiquetas MSS/ MMRp
NCT ID NCT03868228	TitlePIPAC para el tratamiento de las metástasis colorrectales peritoneales	Fase Fase 1	Date Added 2019-03-11	Ubicación Reino Unido	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05319314	TitleGCC19CART for Patients With Metastatic Colorectal Cancer	Fase Fase 1	Date Added 2022-04-08	Ubicación California, United States Colorado, United States Massachusetts, United States Michigan, United States Texas, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas GCC19CART	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02869217	TitleStudy of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors	Fase Fase 1	Date Added 2016-08-16	Ubicación Canadá	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas Cyclophosphamide, Fludarabine, TBI-1301	Etiquetas MSS/ MMRp
NCT ID NCT05194735	TitleEstudio de fase I/II de células T autólogas que expresan receptores de células T (TCR) en sujetos con tumores sólidos	Fase Fase 1	Date Added 2022-01-18	Ubicación Texas, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas Aldesleukin (IL-2), Neoantigen specific TCR-T cell drug product	Etiquetas MSS/ MMRp
NCT ID NCT02888743	TitleDurvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer	Fase Fase 2	Date Added 2016-09-05	Ubicación Arizona, United States California, United States Connecticut, United States Florida, United States Georgia, United States Kentucky, United States Maryland, United States Massachusetts, United States Michigan, United States Minnesota, United States Missouri, United States New Jersey, United States North Carolina, United States Ohio, United States Pennsylvania, United States Tennessee, United States Virginia, United States Wisconsin, United States Canadá	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas durvalumab, Tremelimumab	Etiquetas MSS/ MMRp
NCT ID NCT03545815	TitleEstudio de células CAR-T mediadas por CRISPR-Cas9 con genes PD-1 y TCR knocked out dirigidos a mesotelina en pacientes con tumores sólidos múltiples mesotelina positivos.	Fase Fase 1	Date Added 2018-06-04	Ubicación China	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas células CAR-T anti-mesotelina	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03388632	TitleInterleucina-15 recombinante en combinación con los inhibidores de puntos de control nivolumab e ipilimumab en pacientes con cáncer refractario	Fase Fase 1	Date Added 2018-01-03	Ubicación Maryland, United States	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas Ipilimumab, Nivolumab, rhIL-15, Opdivo, Yervoy	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02484404	TitleEstudio de Fase I/II del Anticuerpo Anti-Ligando de Muerte Programada-1 Durvalumab (MEDI4736) en Combinación con Olaparib y/o Cediranib para Tumores Sólidos Avanzados y Cáncer de Ovario, Mama Triple Negativa, Pulmón, Próstata y Colorrectal Avanzado o Recurrente....	Fase Phase 1, Phase 2	Date Added 2015-06-29	Ubicación Maryland, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas Cediranib, durvalumab, Olaparib	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03547999	TitleA Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC	Fase Fase 2	Date Added 2018-06-06	Ubicación California, United States Florida, United States Kansas, United States New Jersey, United States Ohio, United States Oregon, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas FPV-CV301, mFOLFOX6, MVA-BN-CV301, Nivolumab	Etiquetas MSS/ MMRp

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