Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT06253520	TitleAutologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer	Fase Fase 1	Date Added 2024-02-12	Ubicación Maryland, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas Aldesleukin, Cyclophosphamide, Fludarabine	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06043713	TitleCélulas T transgénicas CD8+ y CD4+ autólogas que expresan receptores de células T específicos de la mutación KRASG12V de alta afinidad (FH-A11KRASG12V-TCR) para el tratamiento de pacientes con cánceres metastásicos de páncreas, colorrectal y de pulmón de células no pequeñas con mutaciones KRAS G12V.	Fase Fase 1	Date Added 2023-09-21	Ubicación Washington, United States	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas Bendamustine, Cyclophosphamide, Fludarabine	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03638206	TitleAutologous CAR-T/TCR-T Cell Immunotherapy for Malignancies	Fase Fase 1/Fase 2	Date Added 2018-08-20	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas CAR-T cell immunotherapy	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05141474	TitleEvaluación de la seguridad y tolerabilidad de la terapia ex vivo con linfocitos infiltrantes de tumor (TIL) seleccionados por neoantígenos de nueva generación en tumores epiteliales avanzados y tumores sólidos resistentes al bloqueo de puntos de control inmunitario (ICB).	Fase Fase inicial 1	Date Added 2021-12-02	Ubicación España	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas Interleukin-2, NEXTGEN-TIL, Non-myeloablative Lymphodepletion (NMA-LD) Regimen	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03832855	TitleEvaluación de la inmunogenicidad de pING-hHER3FL	Fase Fase 1	Date Added 2019-02-06	Ubicación North Carolina, United States	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas pING-hHER3FL	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03829462	TitleEvaluación de una combinación de regorafenib e irinotecán frente a regorafenib solo en pacientes con cáncer colorrectal metastásico	Fase Fase 3	Date Added 2019-02-04	Ubicación Francia	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Irinotecan, Regorafenib	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05464030	TitleAnti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)	Fase Fase 1	Date Added 2022-07-19	Ubicación California, United States Rhode Island, United States Texas, United States Canadá Japón Corea, República de España	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas M9140	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04432857	TitleAN0025 and Pembrolizumab Combination in Advanced Solid Tumors	Fase Fase 1	Date Added 2020-06-16	Ubicación Missouri, United States Texas, United States Utah, United States Virginia, United States Francia	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas AN0025, Pembrolizumab	Etiquetas MSS/ MMRp
NCT ID NCT04660812	TitleAn Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.	Fase Phase 1, Phase 2	Date Added 2020-12-09	Ubicación Alabama, United States Arizona, United States California, United States Connecticut, United States District of Columbia, United States Georgia, United States Louisiana, United States Maryland, United States Missouri, United States Nevada, United States New York, United States Pennsylvania, United States South Carolina, United States Tennessee, United States Texas, United States Wisconsin, United States Francia Italia Corea, República de España Reino Unido	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas AB680, Bevacizumab, Etrumadenant, mFOLFOX-6 regimen, Regorafenib, Zimberelimab	Etiquetas MSS/ MMRp
NCT ID NCT03994601	TitleEstudio de inmunoterapia en investigación de BMS-986288 solo y en combinación con nivolumab en cánceres sólidos avanzados.	Fase Fase 1	Date Added 2019-06-21	Ubicación California, United States Colorado, United States Maryland, United States Missouri, United States New Jersey, United States Argentina Canadá Chile Francia Italia España	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas BMS-986288, Nivolumab, Opdivo	Etiquetas MSI-H/ MMRd, MSS/ MMRp

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