Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT03155061	TitleStudy of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors	Phase Phase 1	Date Added 2017-05-16	Location Japan	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs ONO-4538, ONO-4578, Opdivo	Tags MSS/ MMRp
NCT ID NCT02925234	TitleThe Drug Rediscovery Protocol (DRUP Trial)	Phase Phase 2	Date Added 2016-10-05	Location Netherlands	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs Abemaciclib, afatinib, Alectinib, Alpelisib, Atezolizumab and Bevacizumab, Axitinib, Cabozantinib, Crizotinib, Dabrafenib, Dabrafenib and trametinib, Dacomitinib, durvalumab, Entrectinib, Erdafitinib, Erlotinib, Ipilimumab and nivolumab, Lenvatinib, lorlatinib, Nilotinib, Nivolumab, Olaparib, palbociclib, panitumumab, Pembrolizumab, Regorafenib, ribociclib, Rucaparib, Sunitinib, Talazoparib, Trametinib, Trastuzumab and Pertuzumab (combination treatment), Vemurafenib and Cobimetinib (combination treatment), Vismodegib	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04085185	TitleA Study Evaluating the Safety, Tolerability, and Initial Efficacy of IBI110 in Subjects With Advanced Malignant Tumors	Phase Phase 1	Date Added 2019-09-11	Location China	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs IBI110, IBI110+ Sintilimab, IBI110, Sintilinab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02617277	TitleSafety, Tolerability and Pharmacokinetics of AZD1775 (Adavosertib) Plus MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumours	Phase Phase 1	Date Added 2015-11-30	Location Colorado, United States Florida, United States Tennessee, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs AZD1775, MEDI4736	Tags MSS/ MMRp
NCT ID NCT04550897	TitleA Phase I/II Study With BM7PE Immunotoxin in Colorectal Cancer Patients	Phase Phase 1	Date Added 2020-09-16	Location Norway	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs BM7PE	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03368963	TitleTAS102 in Combination With NAL-IRI in Advanced GI Cancers	Phase Phase 1, Phase 2	Date Added 2017-12-11	Location Georgia, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Nanoliposomal Irinotecan, Trifluridine and Tipiracil Hydrochloride	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05291156	TitleCAVE-2 GOIM Study: a Clinical Study of the Combination of Avelumab Plus Cetuximab as Rechallenge Strategy	Phase Phase 2	Date Added 2022-03-22	Location Italy	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Avelumab, cetuximab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03476681	TitleStudy of NEO-201 in Solid Tumors Expansion Cohorts	Phase Phase 1, Phase 2	Date Added 2018-03-26	Location Maryland, United States Virginia, United States	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs NEO-201 in combination with pembrolizumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID VAPER	TitleA study looking at using a vaccine and chemotherapy to treat advanced cancer	Phase Phase 1	Date Added 2015-11-17	Location	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Celecoxib, Cyclophosphamide, imiquimod, vaccine	Tags MSS/ MMRp
NCT ID NCT03502733	TitleTesting the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma	Phase Phase 1	Date Added 2018-04-19	Location Maryland, United States Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Copanlisib, Ipilimumab, Nivolumab, Aliqopa, Opdivo	Tags MSS/ MMRp

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