We are bringing together scientists, clinicians, industry partners, funders, and research advocates to engage in a series of workshops aimed to address research gaps, identify resources, and develop actionable strategies to predict, prevent, and treat early-age onset colorectal cancer (EAO-CRC). This series will build on the key issues and themes identified during the December 2023 EAO Think Tank and set the stage for further dialogue during an international Think Tank in 2025.