Many Doctors Doing Colorectal Cancer Screening Wrong

FOBT screening saves lives, but only when it is done right. Three out of four primary care doctors did a fecal occult blood test once during an office visit, a method that is ineffective in finding cancer or preventing death from colorectal cancer. One out…

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Diabetics Do Better Right After Colorectal Surgery

In a surprising results, doctors studying surgical complications and hospital deaths after colorectal surgery found that diabetic patients do better than non-diabetics after surgery. There was a 23 percent reduction in deaths after surgery for diabetics and 18 percent fewer complications. Unfortunately, this improvement in…

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High Levels of Gene MACC1 Predicts Colorectal Cancer Spread

German scientists have identified a gene that has higher levels in colon cancer patients whose tumors are destined to spread. By initiating a signaling pathway in the cancer cell, MACC1 (Metastasis-Associated in Colon Cancer 1) promotes faster cell growth and cancer spread  to distant sites…

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Hypertension Clue to Better Outcomes with Avastin

Patients who developed hypertension with Avastin® (bevacizumab) had better response to treatment for colorectal cancer.  More had tumors shrink, and it took significantly longer for their cancer to get worse. In a small Italian study, researchers measured blood pressure in 39 patients receiving Avastin along…

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Changes in Blood Magnesium Levels Predict Response to Erbitux

Hypomagnesemia, or reduced magnesium levels, is a side effect of Erbitux® (cetuximab) treatment.  Patients with colorectal cancer whose blood magnesium dropped the fastest also had the best response to Erbitux given with Camptosar® (irinotecan) . Italian researchers measured magnesium levels for 68 patients before treatment…

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