Tag Archives: young patients

No Difference in Chemotherapy Benefits for Young Patients with Stage II and III Colon Cancer Compared to Those Fifty and Older

Young patients with stage II or III colon cancer get equal benefit from chemotherapy as older patients, and they have similar side effects. Five years after treatment, 67 percent of patients under the age of fifty hadn’t had their cancer spread beyond the colon (recurrence-free interval), the same percentage that applied to patients who were fifty or over. Overall survival and disease-free survival were somewhat better for young patients because they had fewer other reasons for dying.  Overall and disease-free survival reflect patients who are alive five years after beginning treatment.  Neither includes people who have died from any cause, including their cancer.

Young People with Advanced Colorectal Cancer Do As Well with Chemotherapy as Older Patients

When colorectal cancer spreads to other parts of the body, young people under 50 who get chemotherapy benefit as much as those who are older. With drug combinations, there is no difference between those under 50 and those who are 50 and older in responding to chemotherapy, how long it takes before cancer gets worse, or in survival time.

Young Patients Do Worse After Surgery for Liver Mets

Patients under 40 appear to have more aggressive liver tumors from colorectal cancer and poorer long-term outcomes. After surgery to remove the cancer that had spread to their liver, patients who were 40 or younger had poorer overall survival and shorter time until cancer returned. The percentage of younger patients who were alive without cancer five years later was similar to older patients, which the research team attributed to more aggressive treatment for the young patients, along with repeated surgery. 

Incidence of Rectal Cancer Increasing in Patients under Forty

Update from the 2009 Gastrointestinal Cancer Symposium Incidence of rectal cancer in younger patients is increasing, although there is no similar pattern with colon cancer or in older rectal cancer patients.  The reason for the trend is unclear. First observed in a single cancer center, the trend toward more rectal cancer in patients under forty was confirmed in review of the Surveillance Epidemiology and End Results (SEER) database.