Rally on Research: Early-Age Onset Colorectal Cancer On June 24 and 25, experts and patient advocates from around the world met virtually to share ideas and forge the path towards a cure for colorectal cancer. ABOUT THE 2021 EVENT Share on Facebook Share on LinkedIn Share on Twitter Copy this URL Share via Email Early-Age Onset Colorectal Cancer Colorectal cancer is no longer a disease that only affects older populations. Early-age onset CRC is colorectal cancer diagnosed in a patient younger than age 50, and commonly referred to as “EAO CRC.” These patients and survivors face issues specific to younger populations, such as sexual health and family planning, as well as impacts to their careers. Learn More Rally on Research is an interactive two-day virtual event, inspired and co-hosted by Dr. José Perea of Madrid, Spain. The event is created for relentless champions to engage with other researchers, clinicians, and patient advocates to build a path toward a cure for early-age onset colorectal cancer (EAO CRC). jump to advocacy abstracts jump to scientific abstracts jump to resources Day 1: Patient Advocates 11AM - 3:30PM EST Designed to amplify the patient voice, this was an opportunity for patients, caregivers, and clinicians to discuss efforts and challenges to improve patient care for the early-age onset community. Opening Remarks from Fight CRC President, Anjee Davis Patient and Caregiver Panel Clinician Panel Closing Remarks Day 2: Research Priorities 11AM - 3:30PM EST Day 2 was a global research discussion among scientists who want to work together to advance research to understand and treat early-age onset colorectal cancer. This day was designed to ensure researchers and healthcare providers have time to discuss research needs and bridge gaps from a scientific perspective. Day 2 Welcome and Kickoff EAO CRC Workgroup Project Showcase CRC Screening Guidelines Panel Treatment and Care Delivery Panel Funder's Corner EAO CRC Disparities: Society Meets Biology Closing Remarks Breakout Sessions Gut Microbiome Breakout Session Germline Somatic Tumor Testing Breakout Session Molecular Pathways Breakout Session Immunotherapies Breakout Session Caregiving Breakout Session Provider Education for Diagnosis Breakout Session Donate to Research We can't make progress and save lives without groundbreaking research. That requires funds from generous supporters like you. Every dollar counts. Make a Donation Abstracts Advocacy COLONTOWN University: Novel CRC Patient Education Resources for Patient Empowerment Nancy Seybold; Manju George, DVM, PhD; Susan WysokiPALTOWN Development Foundation, United States, COLONTOWN, United States Poster Presentation download poster Never Too Young: Early-Age Onset Patient and Caregiver Experiences in Canada Elle Doherty, MPH, CHE; Iris KarryColorectal Cancer Canada, Canada Poster Presentation download poster Awareness Drives Preventative Screening Coverage for Employees Michael Mancini, Patient Advocate, United States Poster Presentation Sharing Actual Patient Experience in Understanding, Searching, Matching, Enrolling, and Participating in Clinical Trials Jessica Buscho, Patient Advocate, United States Poster Presentation download poster Raising awareness, challenging perceptions and motivating action to address Australia’s rising rates of early-age onset bowel cancer Joni Thomes, Bowel Cancer Australia, Australia Poster Presentation download poster Early Age Onset CRC & My Research Advocacy Efforts and Contributions Wenora Johnson, Patient Advocate, United States Poster Presentation download poster On-Call Allies: A More Tailored Approach to Colorectal Cancer Patient Support Andrea Bauer, Michelle Cappel, Vanessa Ghigliotty, Allison RosenPatient Advocates, United States download poster Improving Quality of Life by Incorporating Properly Trained Ostomy Peers to Provide Education Support and Non-Clinical Care into Treatment Debi Fox, Ostomy 2-1-1, United States download poster Scientific Majority of patients undergoing colorectal cancer resection 2010-2018 have not participated in colorectal screening programs Carmen Fong, MD; Dimitri F. Joseph; Ellen Li, MD; Paula Denoya, MDMount Sinai Hospital, United StatesStony Brook University School of Medicine, United States download poster Molecular and clinical characterization of Brazilian early-age onset colorectal cancer patients Giovana Tardin Torrezan, Sara Iolanda Oliveira da Silva, Bruna Elisa Katin Kupper, Karina Miranda Santiago, Samuel Aguiar, Maria Nirvana Formiga, Dirce Maria Carraro A.C. Camargo Cancer Center, Brazil Familial Component of Early-Onset Colorectal Cancer in Europe: An Opportunity for Disease Prevention Maria Daca Alvarez, Marc Martí, Antonino Spinelli, Marek Szczepkowski, Wieslaw Tarnowski, Omar Faiz, Kevin Monahan, Silviu-Tiberiu Makkai-Popa, Noel de Miranda, Claire Palles, Sirio Melone, Fernando Jiménez, Elena Hurtado, Marta Jiménez, IsabelPrieto, Araceli Ballestero, José A. Alcazar, Alfredo Vivas, Lorena Brandáriz, Irene López, Edurne Álvaro, Teresa Ocaña, Lorena Moreno, Sabela Carballal, Leticia Moreira, Maria Pellisé, Andreana N. Holowatyj, José Perea, Francesc Balaguer Gastroenterology Department, Hospital Clínic de Barcelona, SpainHospital Universitario Vall d'Hebron, Barcelona, SpainHospital Humanitas, Milan, ItalyBielanski Hospital, Warsaw, PolandOrlowski Hospital, Warsaw, PolandSt. Mark's Hospital, London, United KingdomWest Middlesex University Hospital, London, United KingdomCentre Hospitalier de Luxembourg, LuxembourgLeiden University Medical Center, Leiden, NetherlandsBirmingham University, Birmingham, United KingdomHospital Universitario Fundación Alcorcón, Madrid, SpainHospital Galdakao-Usansolo, Vizcaya, SpainHospital Universitario Gregorio Marañon, SpainHospital del Mar, Barcelona, SpainHospital Universitario La Paz, Madrid, SpainHospital Universitario Ramon y Cajal, Madrid, SpainHospital Universitario de Salamanca, Salamanca, SpainHospital Universitario 12 de Octubre, Madrid, SpainHospital Universitario General de Villalba, Madrid, SpainHospital MD Anderson, Madrid, SpainHospital Universitario Infanta Leonor, Madrid, SpainVanderbilt University Medical Center, Nashville, Tennessee, United StatesHospital Universitario Fundación Jiménez Díaz, Madrid, Spain download slides Comparative analysis of tumor characteristics and oncologic outcomes of patients with early-versus late-onset rectal cancer Sara Tamburello, Caterina Foppa, Michele Carvello, Luigi Laghi, Laura Poliani, Armando Santoro, Valeria Smiroldo, Cristiana Bonifacio, Marco Montorsi, Annalisa Maroli, Antonino Spinelli IRCCS Humanitas Research Hospital, Milan, Italy Poster Presentation download poster Is early-onset colorectal cancer different according to disease location? Analysis of tumor characteristics, risk factors and clinical outcomes of 385 genetically tested patients Caterina Foppa, Sara Tamburello, Michele Carvello, Luigi Laghi, Laura Poliani, Armando Santoro, Valeria Smiroldo, Cristiana Bonifacio, Annalisa Maroli, Antonino SpinelliIRCCS Humanitas Research Hospital, Milan, Italy Poster Presentation download poster Characterizing the burden of early onset colorectal cancers in Africa: a systematic review and meta-analysis Nicholas Matovu, Helen G. Coleman, Chris R. Cardwell, Ines Mesa-Eguiagaray, Evropi Theodoratou, Charlene M. McShane; Centre for Public HealthQueen’s University Belfast, Belfast, UKPatrick G Johnston Centre for Cancer ResearchCentre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UKCancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK Poster Presentation download poster Sexual dysfunction among young adult colorectal cancer survivors Julia Stal, BA; Serena Yi, BSc.; Sally Cohen-Cutler, MD, MS; Phuong Gallagher, BS; Afsaneh Barzi, MD, PhD; David R. Freyer, DO, MS; Jonathan N. Kaslander, MArch; Martina Anto-Ocrah, PhD; Heinz-Josef Lenz, MD; Kimberly A. Miller, PhD, MPH Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USACancer and Blood Disease Institute, Children’s Hospital Los Angeles, Los Angeles, CA, USAThe Colon Club, USADepartment of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, California, USADepartment of Pediatrics, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USAUSC Norris Comprehensive Cancer Center, Los Angeles, CA, USADepartments of Emergency Medicine, ObGyn, and Neurology, University of Rochester Medical Center, Rochester, NY, USADivision of Oncology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USADepartment of Dermatology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA download poster Genetic analysis of SMAD4 C-terminal domain in patients with microsatellite stable early-age onset colorectal cancer Jovana Despotovic, Tamara Babic, Zoran Krivokapic, Aleksandra Nikolic Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, SerbiaFaculty of Medicine, University of Belgrade, Belgrade, SerbiaFirst Surgical Clinic, Clinical Center of Serbia, Belgrade, SerbiaSerbian Academy of Sciences and Arts, Belgrade, Serbia Poster Presentation Establishing a Coordinated Clinical Center for Young Onset Colorectal Cancer Melissa Lumish, Lerie Palmaira, Joseph Bacani, Asha Krishnan, Jill Weiss, Rosemary Semler, Anne Casson, Ashley Arkema, Jeanne Carter, Christian Nelson, John Mulhall, Julio Garcia-Aguilar, Zsofia Stadler, Robin Mendelsohn, Andrea Cercek Memorial Sloan Kettering Cancer Center, United States Poster Presentation download poster Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women Jinhee Hur, Ebunoluwa Otegbeye, Hee-Kyung Joh, Katharina Nimptsch, Kimmie Ng, Shuji Ogino, Jeffrey A. Meyerhardt, Andrew T.Chan, Walter C. Willett, Kana Wu, Edward Giovannucci, Yin Cao Department of Nutrition, Harvard T.H. Chan School of Public Health, United StatesDepartment of Surgery, Washington University School of Medicine, United StatesDepartment of Medicine, Seoul National University College of Medicine, South KoreaMolecular Epidemiology Research Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, GermanyDepartment of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, United StatesProgram in Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, United StatesDepartment of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, United StatesClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, United StatesDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, United States Poster Presentation Methylated Septin9 (mSEPT9) is a promising biomarker for the early detection and screening of early-onset colorectal cancer Holli A. Loomans-Kropp, Yurong Song, Manish Gala, Aparna R. Parikh, Emily Van Seventer, Rocio Alvarez, Megan P. Hitchins, Robert H. Shoemaker, Asad Umar National Cancer Institute, United StatesFrederick National Laboratory for Cancer Research, United StatesMassachusetts General Hospital, United StatesCedars-Sinai Medical Center, United States Genetics of early onset colorectal cancers Helen Curley, Silver Makepeace, Sarah Briggs, Lynn Martin, Ian Tomlinson, Claire Palles Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UKCentre for Computational Biology, University of Birmingham, Birmingham, UKWellcome Trust Centre for Human Genetics, University of Oxford, Edinburgh Cancer Research Centre, IGMM, University of Edinburgh, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK download poster Resources Program Documents Speaker and Moderator Bios Advocacy and Scientific Abstracts Fight CRC Resources Survivorship Care Planning Clinical Trial Finder Resource Library Organizations and Programs American Cancer Society Bowel Cancer Australia Bowel Cancer UK Colorectal Cancer Canada Never Too Young Patient & Caregiver Survey Report Colorectal Cancer Resource and Action Network (Canada) Digestive Cancers Europe Europa Colon Italia Onlus Lynch Syndrome Ireland Spanish Association Against Cancer (AECC) Funding Entities CDC - CRCCP CDC Colorectal Cancer Resources, including Screen for Life “Birds and the Bums” PSA focused on screening at age 45 Department of Defense – Peer Reviewed Cancer Research Program (PRCRP) National Cancer Institute Funding Opportunities NCI and Cancer Research UK Cancer Grand Challenges Additional Resources United Ostomy Associations of America Support Group Finder Ostomy 2-1-1 Living with Cancer: A Report on the Patient Experience History of the Event In 2019, Dr. José Perea, a colorectal cancer researcher in Madrid, Spain, shared his vision for an international research symposium that would bring together the sharpest minds focused on early-onset colorectal cancer (also called EAO CRC) with Fight CRC. A strong partnership was formed and the inaugural EAO CRC International Symposium was developed. The initial event in Denver, Colorado hosted 45 attendees from 4 countries. From this event, the Fight CRC EAO CRC Workgroup was formed. In 2020, the 2nd-annual symposium became a virtual event and grew to more than 500 registrants from 17 countries. In planning for our third year, our vision grew bigger. We wanted to include the patient voice in discussions and build a bridge between researchers, clinicians, and advocates. We felt it was imperative to create an engaging space to listen and learn from one another. To reflect our vision and growth, we renamed the annual event to Rally on Research. In 2021, we will rally to continue discussing EAO CRC and paving a collaborative path forward. Watch the 2020 Event 2020 EAO CRC International Symposium learn more about our eao crc workgroup Thank You to Our Sponsors International Advocacy and Research Partners